Synthesis and characterization of macroporous chitosan/calcium phosphate composite scaffolds for tissue engineering

Author(s):  
Yong Zhang ◽  
Miqin Zhang
2017 ◽  
Vol 758 ◽  
pp. 199-203
Author(s):  
Florian Olivier ◽  
Q. Picard ◽  
S. Delpeux ◽  
F. Fayon ◽  
J. Chancolon ◽  
...  

Calcium phosphate (CaP) ceramics, e.g. hydroxyapatite Ca10(PO4)6(OH)2 (HAP) and tricalcium phosphate Ca3(PO4)2 (TCP), are widely employed in the field of bone tissue engineering due to their controlled biodegradability and excellent biocompatibility. In the present study, the chemical composition, microtexture and structure of CaP deposits on carbon fiber cloths (CFC) are investigated. Coatings of CaP or strontium-substituted calcium phosphate (Sr-CaP) on CFC are obtained by sono-electrodeposition process using cathodic polarization. At constant potential, the deposits consist in a biomimetic carbonated calcium-deficient hydroxyapatite (CaD-HAP), having a plate-like morphology with the possibility to control the Sr2+ incorporation. In orthopaedic field, CaP or Sr-CaP coated carbon fiber cloths offer new promising bioceramic materials for bone repair and regeneration.


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